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Most notably, she got the alleged IRA bombers, the Guildford Four and the Birmingham Six, freed after being in jail for 14 and 16 years respectively.
Her intervention led to Judith Ward, another supposed IRA bomber, getting her conviction quashed. And she won freedom for Frank Johnson after he served 26 years for murder.
She has defended terrorist suspects in the UK and Guantanamo Bay and represented the family of Jean Charles de Menezes, the alleged terrorist shot dead by police in London. In the 1980s she opposed the detention of striking miners.
Now in her sixties, she is a notoriously private person who consistently refuses interviews and publicity and works tirelessly to right miscarriages of justice. She treats those she represents as personal friends and not with the usual professional detachment.
It is said that it was her work as a journalist in the USA during the Civil Rights Movement that created her passion for human rights.
She is absolutely tenacious about her cases and refuses to give up however daunting the legal difficulties. If necessary she works 12 hour days to get at the truth.
Her extreme dedication is astonishing in a profession where lawyers are not always conscientious about their work and may turn up to court knowing little or nothing about their client's case. She finds such behaviour quite unforgivable. If only there were more like her, fewer innocent people would be languishing in jail.
Footnote: In the film about the Guildford Four, 'In the Name of the Father', Gareth Peirce was played by Emma Thompson.